Ontology highlight
ABSTRACT:
SUBMITTER: Richter P
PROVIDER: S-EPMC10572174 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Richter Patricia P Macovei Luana Andreea LA Mihai Ioana Ruxandra IR Cardoneanu Anca A Burlui Maria Alexandra MA Rezus Elena E
International journal of molecular sciences 20230922 19
Systemic lupus erythematosus (SLE) is an autoimmune disorder known for its complex pathogenesis, in which cytokines play an essential role. It seems that the modulation of these cytokines may impact disease progression, being considered potential biomarkers. Thus, TNF (tumor necrosis factor)-α and IL (interleukin)-17 are molecules of great interest in SLE. TNF-α plays a dual role in SLE, with both immunosuppressive and proinflammatory functions. The role of IL-17 is clearly described in the path ...[more]