Ontology highlight
ABSTRACT:
SUBMITTER: Mellett L
PROVIDER: S-EPMC10580308 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Mellett Leah L Amarasinghe Gaya G Farnsworth Christopher W CW Khader Shabaana A SA
ACS infectious diseases 20231003 10
The alarmin calprotectin (S100A8/A9) is thought to drive a cytokine storm, a hallmark of severe COVID-19. Recent studies report circulating S100A8/A9 levels can distinguish COVID-19 severity but have only been conducted in non-U.S. cohorts and mainly focus on serum S100A8/A9 levels. Thus, we quantified S100A8/A9 in serum and urine samples from a hospital cohort in St. Louis, Missouri, to expand the understanding of S100A8/A9 as a prognostic biomarker for COVID-19. Elevated S100A8/A9 serum levels ...[more]