Ontology highlight
ABSTRACT:
SUBMITTER: Vasiukov G
PROVIDER: S-EPMC10582049 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Vasiukov Georgii G Zou Yong Y Senosain Maria-Fernanda MF Rahman Jamshedur S M JSM Antic Sanja S Young Katherine M KM Grogan Eric L EL Kammer Michael N MN Maldonado Fabien F Reinhart-King Cynthia A CA Massion Pierre P PP
Scientific reports 20231017 1
Lung adenocarcinoma (LUAD) is the predominant type of lung cancer in the U.S. and exhibits a broad variety of behaviors ranging from indolent to aggressive. Identification of the biological determinants of LUAD behavior at early stages can improve existing diagnostic and treatment strategies. Extracellular matrix (ECM) remodeling and cancer-associated fibroblasts play a crucial role in the regulation of cancer aggressiveness and there is a growing need to investigate their role in the determinat ...[more]