Dataset Information

Cow's milk-related symptom score (CoMiSS): from Bristol to Brussels Stool Scale.

ABSTRACT:

Objectives

The Cow's Milk-related Symptom Score (CoMISS TM) is an awareness tool for evaluating cow's milk-related symptoms in otherwise healthy infants <1 year of age. This study assessed whether replacing the Bristol Stool Form Scale (BSFS) with the Brussels Infants and Toddlers Stool Scale (BITSS) in non-toilet-trained infants would modify the overall CoMiSS and change the clinical approach regarding potential cow's milk allergy.

Methods

Non-toilet-trained infants aged <13 months were assessed by CoMiSS using the seven images from the BSFS (CoMiSS-BSFS) compared to the four images of stools from BITSS (CoMiSS-BITSS). The Wilcoxon Signed-Rank test and Pearson Correlation Coefficient were calculated. A post hoc analysis using identical tests was performed in subsets of CoMiSS-BSFS scores ≥10, ≥12, ≤5 and ≥6.

Results

844 pairwise scores were collected. Applying the Wilcoxon test over the complete dataset, the difference between CoMiSS-BSFS and CoMiSS-BITSS was statistically significant (p<0.001). However, there was no significant difference in the subsets with CoMiSS-BSFS ≥10, ≥12 and ≥6 (p=0.84, p=0.48 and p=0.81, respectively). The significant difference remained restricted to the group with CoMiSS-BSFS ≤5, considered at low risk for CM-related symptoms (p<0.001).

Conclusion

Replacing BSFS with BITSS does not change the cut-off for awareness of possible CM-related symptoms and will not impact the use of CoMiSS in clinical practice. Changes in CoMiSS remained limited to the subgroup with a low risk for CM-related symptoms.

SUBMITTER: Bajerova K

PROVIDER: S-EPMC10583930 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature

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Publications

Cow's Milk-Related Symptom Score (CoMiSS): From Bristol to Brussels Stool Scale.

Bajerova Katerina K Salvatore Silvia S Dupont Christophe C Kuitunen Mikael M Meyer Rosan R Ribes-Koninckx Carmen C Shamir Raanan R Szajewska Hania H Staiano Annamaria A Vandenplas Yvan Y

Journal of pediatric gastroenterology and nutrition 20230906 5

<h4>Objectives</h4>The Cow's Milk-related Symptom Score (CoMISS) is an awareness tool for evaluating cow's milk-related symptoms in otherwise healthy infants <1 year of age. This study assessed whether replacing the Bristol Stool Form Scale (BSFS) with the Brussels Infants and Toddlers Stool Scale (BITSS) in non-toilet-trained infants would modify the overall CoMiSS and change the clinical approach regarding potential cow's milk allergy.<h4>Methods</h4>Non-toilet-trained infants aged <13 months ...[more]

PMID: 37668589

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