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Molecular characterization of a TEM-21 beta-lactamase in a clinical isolate of Morganella morganii.


ABSTRACT: A clinical isolate of Morganella morganii, with reduced susceptibility to expanded-spectrum cephalosporins and aztreonam, was found to produce an extended-spectrum beta-lactamase with a pI of 6.4. The nucleotide sequence of the encoding gene was that of the gene encoding TEM-21. This is the first molecular characterization of an extended-spectrum beta-lactamase in M. morganii.

SUBMITTER: Tessier F 

PROVIDER: S-EPMC105882 | biostudies-literature | 1998 Aug

REPOSITORIES: biostudies-literature

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Molecular characterization of a TEM-21 beta-lactamase in a clinical isolate of Morganella morganii.

Tessier F F   Arpin C C   Allery A A   Quentin C C  

Antimicrobial agents and chemotherapy 19980801 8


A clinical isolate of Morganella morganii, with reduced susceptibility to expanded-spectrum cephalosporins and aztreonam, was found to produce an extended-spectrum beta-lactamase with a pI of 6.4. The nucleotide sequence of the encoding gene was that of the gene encoding TEM-21. This is the first molecular characterization of an extended-spectrum beta-lactamase in M. morganii. ...[more]

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