Ontology highlight
ABSTRACT:
SUBMITTER: Estiri H
PROVIDER: S-EPMC10616090 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Estiri Hajar H Bhattacharya Shapla S Buitrago Jhon Alexander Rodriguez JAR Castagna Rossella R Legzdiņa Linda L Casucci Giorgia G Ricci Andrea A Parisini Emilio E Gautieri Alfonso A
Scientific reports 20231030 1
Fructosyl peptide oxidases (FPOX) are deglycating enzymes that find application as key enzymatic components in diabetes monitoring devices. Indeed, their use with blood samples can provide a measurement of the concentration of glycated hemoglobin and glycated albumin, two well-known diabetes markers. However, the FPOX currently employed in enzymatic assays cannot directly detect whole glycated proteins, making it necessary to perform a preliminary proteolytic treatment of the target protein to g ...[more]