Identification of urinary volatile organic compounds as a potential non-invasive biomarker for esophageal cancer.
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ABSTRACT:
SUBMITTER: Liu Q
PROVIDER: S-EPMC10616168 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Publications
Identification of urinary volatile organic compounds as a potential non-invasive biomarker for esophageal cancer.
Liu Qi Q Li Shuhai S Li Yaping Y Yu Longchen L Zhao Yuxiao Y Wu Zhihong Z Fan Yingjing Y Li Xinyang X Wang Yifeng Y Zhang Xin X Zhang Yi Y
Scientific reports 20231030 1
Early diagnosis of esophageal cancer (EC) is extremely challenging. The study presented herein aimed to assess whether urinary volatile organic compounds (VOCs) may be emerging diagnostic biomarkers for EC. Urine samples were collected from EC patients and healthy controls (HCs). Gas chromatography-ion mobility spectrometry (GC-IMS) was next utilised for volatile organic compound detection and predictive models were constructed using machine learning algorithms. ROC curve analysis indicated that ...[more]
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