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The Burden and Treatment of Chronic Constipation Among US Nursing Home Residents.


ABSTRACT:

Objective

To evaluate the burden of chronic constipation (CC) and the use of drugs to treat constipation (DTC) in 2 complementary data sources.

Design

Retrospective cohort study.

Setting and participants

US nursing home residents aged ≥65 years with CC.

Methods

We conducted 2 retrospective cohort studies in parallel using (1) 2016 electronic health record (EHR) data from 126 nursing homes and (2) 2014-2016 Medicare claims, each linked with the Minimum Data Set (MDS). CC was defined as (1) the MDS constipation indicator and/or (2) chronic DTC use. We described the prevalence and incidence rate of CC and the use of DTC.

Results

In the EHR cohort, we identified 25,739 residents (71.8%) with CC during 2016. Among residents with prevalent CC, 37% received a DTC, with an average duration of use of 19 days per resident-month during follow-up. The most frequently prescribed DTC classes included osmotic (22.6%), stimulant (20.9%), and emollient (17.9%) laxatives. In the Medicare cohort, a total of 245,578 residents (37.5%) had CC. Among residents with prevalent CC, 59% received a DTC and slightly more than half (55%) were prescribed an osmotic laxative. Duration of use was shorter (10 days per resident-month) in the Medicare (vs EHR) cohort.

Conclusions and implications

The burden of CC is high among nursing home residents. The differences in the estimates between the EHR and Medicare data confirm the importance of using secondary data sources that include over-the-counter drugs and other treatments unobservable in Medicare Part D claims to assess the burden of CC and DTC use in this population.

SUBMITTER: Zhang T 

PROVIDER: S-EPMC10642798 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature

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Publications

The Burden and Treatment of Chronic Constipation Among US Nursing Home Residents.

Zhang Tingting T   Zullo Andrew R AR   James Hannah O HO   Lee Yoojin Y   Taylor Douglas C A DCA   Daiello Lori A LA  

Journal of the American Medical Directors Association 20230609 8


<h4>Objective</h4>To evaluate the burden of chronic constipation (CC) and the use of drugs to treat constipation (DTC) in 2 complementary data sources.<h4>Design</h4>Retrospective cohort study.<h4>Setting and participants</h4>US nursing home residents aged ≥65 years with CC.<h4>Methods</h4>We conducted 2 retrospective cohort studies in parallel using (1) 2016 electronic health record (EHR) data from 126 nursing homes and (2) 2014-2016 Medicare claims, each linked with the Minimum Data Set (MDS).  ...[more]

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