Ontology highlight
ABSTRACT:
SUBMITTER: Pouyabahar D
PROVIDER: S-EPMC10651689 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Pouyabahar Delaram D Chung Sai W SW Pezzutti Olivia I OI Perciani Catia T CT Wang Xinle X Ma Xue-Zhong XZ Jiang Chao C Camat Damra D Chung Trevor T Sekhon Manmeet M Manuel Justin J Chen Xu-Chun XC McGilvray Ian D ID MacParland Sonya A SA Bader Gary D GD
iScience 20231014 11
The large size and vascular accessibility of the laboratory rat (<i>Rattus norvegicus</i>) make it an ideal hepatic animal model for diseases that require surgical manipulation. Often, the disease susceptibility and outcomes of inflammatory pathologies vary significantly between strains. This study uses single-cell transcriptomics to better understand the complex cellular network of the rat liver, as well as to unravel the cellular and molecular sources of inter-strain hepatic variation. We gene ...[more]