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Direct observation of adaptive tracking on ecological time scales in Drosophila.

ABSTRACT: Direct observation of evolution in response to natural environmental change can resolve fundamental questions about adaptation, including its pace, temporal dynamics, and underlying phenotypic and genomic architecture. We tracked the evolution of fitness-associated phenotypes and allele frequencies genome-wide in 10 replicate field populations of Drosophila melanogaster over 10 generations from summer to late fall. Adaptation was evident over each sampling interval (one to four generations), with exceptionally rapid phenotypic adaptation and large allele frequency shifts at many independent loci. The direction and basis of the adaptive response shifted repeatedly over time, consistent with the action of strong and rapidly fluctuating selection. Overall, we found clear phenotypic and genomic evidence of adaptive tracking occurring contemporaneously with environmental change, thus demonstrating the temporally dynamic nature of adaptation.

SUBMITTER: Rudman SM

PROVIDER: S-EPMC10684103 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature

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Direct observation of adaptive tracking on ecological time scales in <i>Drosophila</i>.

Rudman Seth M SM Greenblum Sharon I SI Rajpurohit Subhash S Betancourt Nicolas J NJ Hanna Jinjoo J Tilk Susanne S Yokoyama Tuya T Petrov Dmitri A DA Schmidt Paul P

Science (New York, N.Y.) 20220318 6586

Direct observation of evolution in response to natural environmental change can resolve fundamental questions about adaptation, including its pace, temporal dynamics, and underlying phenotypic and genomic architecture. We tracked the evolution of fitness-associated phenotypes and allele frequencies genome-wide in 10 replicate field populations of <i>Drosophila melanogaster</i> over 10 generations from summer to late fall. Adaptation was evident over each sampling interval (one to four generation ...[more]

PMID: 35298245

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Project description:ImportanceParent recall is the primary method for measuring positioning practices such as tummy time in infants. Concerns regarding the accuracy of parent recall have been raised in the literature. To date, no study has examined the agreement of tummy time recall measures with gold-standard methods.ObjectiveTo assess the agreement between parental recall versus direct observation of tummy time in infants, and to explore the impact of prematurity on this relationship.DesignCross-sectional observational study, spanning 1 yr.SettingParticipants' homes Participants: Thirty-two infant-parent dyads (19 full-term, 13 preterm), with infants ages 3 to 6 mo and caregivers ages older than 18 yr.Outcome and measuresHome-recorded videos of infant play across 3 days were used as a proxy for direct observation of tummy time and compared with a 12-item parent recall survey.ResultsParent recall had a significant moderate correlation (ρ = .54, p = .002) with direct observation in full-term infants but was not correlated (p = .23) with direct observation in preterm infants. On average, parents of preterm infants overestimated tummy time by 2.5 times per day compared with direct observation.Conclusions and relevanceFor full-term infants, parent recall measures of tummy time exhibit an acceptable level of agreement with direct observation and can be reliably used over shorter periods. Parents of preterm infants may display a bias in recalling tummy time, leading to overestimations. To accurately assess tummy time in this population, a combination of subjective and objective measures should be explored. Plain-Language Summary: Tummy time is an essential movement experience for infants, especially for preterm infants, who are at a higher risk for motor delays. The most common way to track tummy time is through parent reports, or recall, versus a practitioner directly observing tummy time in the home. Despite the widespread use of parent recall to track tummy time, no study has examined the accuracy of parent recall versus direct observation in the home. Accurately assessing tummy time is crucial for improving and supporting health outcomes for infants. This study found that prematurity may affect the accuracy of parent recall for assessing tummy time in young infants. The authors discuss the implications of this finding and provide suggestions to guide the selection of appropriate methods to measure tummy time in clinical practice and research studies.

Dataset Information

Direct observation of adaptive tracking on ecological time scales in Drosophila.

Publications

Direct observation of adaptive tracking on ecological time scales in <i>Drosophila</i>.

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