Ontology highlight
ABSTRACT:
SUBMITTER: Padron E
PROVIDER: S-EPMC1069529 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Journal of virology 20050401 8
Adeno-associated virus (AAV) is a member of the Parvoviridae, belonging to the Dependovirus genus. Currently, several distinct isolates of AAV are in development for use in human gene therapy applications due to their ability to transduce different target cells. The need to manipulate AAV capsids for specific tissue delivery has generated interest in understanding their capsid structures. The structure of AAV type 4 (AAV4), one of the most antigenically distinct serotypes, was determined to 13-A ...[more]