Ontology highlight
ABSTRACT:
SUBMITTER: Plagge A
PROVIDER: S-EPMC1069615 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Plagge Antonius A Isles Anthony R AR Gordon Emma E Humby Trevor T Dean Wendy W Gritsch Sabine S Fischer-Colbrie Reiner R Wilkinson Lawrence S LS Kelsey Gavin G
Molecular and cellular biology 20050401 8
Genomic imprinting results in parent-of-origin-dependent monoallelic expression of selected genes. Although their importance in development and physiology is recognized, few imprinted genes have been investigated for their effects on brain function. Gnas is a complex imprinted locus whose gene products are involved in early postnatal adaptations and neuroendocrine functions. Gnas encodes the stimulatory G-protein subunit Gsalpha and two other imprinted protein-coding transcripts. Of these, the N ...[more]