Ontology highlight
ABSTRACT:
SUBMITTER: Malorny B
PROVIDER: S-EPMC107023 | biostudies-literature | 1998 Mar
REPOSITORIES: biostudies-literature
Journal of bacteriology 19980301 5
The sequence diversity of 45 Opa outer membrane proteins from Neisseria meningitidis, Neisseria gonorrhoeae, Neisseria sicca, and Neisseria flava indicates that horizontal genetic exchange of opa alleles has been rare between these species. A two-dimensional structural model containing four surface-exposed loops was constructed based on rules derived from porin crystal structure and on conservation of sequence homology within transmembrane beta-strands. The minimal continuous epitopes recognized ...[more]