Ontology highlight
ABSTRACT:
SUBMITTER: Otani Y
PROVIDER: S-EPMC10717848 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Otani Yusuke Y Yoshikawa Soichiro S Nagao Kei K Tanaka Takehiro T Toyooka Shinichi S Fujimura Atsushi A
The journal of physiological sciences : JPS 20231012 1
Mast cells are present in mucosal and connective tissues throughout the body. They synthesize and release a wide variety of bioactive molecules, such as histamine, proteases, and cytokines. In this study, we found that a population of connective tissue mast cells (CTMCs) stores and releases noradrenaline, originating from sympathetic nerves. Noradrenaline-storing cells, not neuronal fibers, were predominantly identified in the connective tissues of the skin, mammary gland, gastrointestinal tract ...[more]