Ontology highlight
ABSTRACT:
SUBMITTER: Simone R
PROVIDER: S-EPMC10724253 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Simone Raffaella R Čižmár Daniel D Holtze Susanne S Michel Geert G Sporbert Anje A Okolo Charlotte C Hildebrandt Thomas B TB
Scientific reports 20231215 1
The African naked mole-rat (Heterocephalus glaber) is an attractive model for cancer and aging research due to its peculiar biological traits, such as unusual long life span and resistance to cancer. The establishment of induced pluripotent stem cells (iPSCs) would be a useful tool for in vitro studies but, in this species, the reprogramming of somatic cells is problematic because of their stable epigenome. Therefore, an alternative approach is the derivation of embryonic stem cells from in vitr ...[more]