Ontology highlight
ABSTRACT:
SUBMITTER: Dura-Bernal S
PROVIDER: S-EPMC10727489 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Dura-Bernal Salvador S Griffith Erica Y EY Barczak Annamaria A O'Connell Monica N MN McGinnis Tammy T Moreira Joao V S JVS Schroeder Charles E CE Lytton William W WW Lakatos Peter P Neymotin Samuel A SA
Cell reports 20231103 11
We developed a detailed model of macaque auditory thalamocortical circuits, including primary auditory cortex (A1), medial geniculate body (MGB), and thalamic reticular nucleus, utilizing the NEURON simulator and NetPyNE tool. The A1 model simulates a cortical column with over 12,000 neurons and 25 million synapses, incorporating data on cell-type-specific neuron densities, morphology, and connectivity across six cortical layers. It is reciprocally connected to the MGB thalamus, which includes i ...[more]