Race and Ethnicity of Infants Enrolled in Neonatal Clinical Trials: A Systematic Review.

ABSTRACT:

Importance

Representativeness of populations within neonatal clinical trials is crucial to moving the field forward. Although racial and ethnic disparities in research inclusion are well documented in other fields, they are poorly described within neonatology.

Objective

To describe the race and ethnicity of infants included in a sample of recent US neonatal clinical trials and the variability in this reporting.

Evidence review

A systematic search of US neonatal clinical trials entered into Cochrane CENTRAL 2017 to 2021 was conducted. Two individuals performed inclusion determination, data extraction, and quality assessment independently with discrepancies adjudicated by consensus.

Findings

Of 120 studies with 14 479 participants that met the inclusion criteria,

SUBMITTER: Lyle ANJ 

PROVIDER: S-EPMC10739112 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature