Expression of Human L-Dopa Decarboxylase (DDC) under Conditions of Oxidative Stress.
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ABSTRACT:
SUBMITTER: Lotsios NS
PROVIDER: S-EPMC10742706 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
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Expression of Human L-Dopa Decarboxylase (DDC) under Conditions of Oxidative Stress.
Lotsios Nikolaos S NS Arvanitis Nikolaos N Charonitakis Alexandros G AG Mpekoulis George G Frakolaki Efseveia E Vassilaki Niki N Sideris Diamantis C DC Vassilacopoulou Dido D
Current issues in molecular biology 20231216 12
Oxidative stress is known to influence mRNA levels, translation, and proteolysis. The importance of oxidative stress has been demonstrated in several human diseases, including neurodegenerative disorders. L-Dopa decarboxylase (DDC) is the enzyme that converts L-Dopa to dopamine (DA). In spite of a large number of studies, little is known about the biological significance of the enzyme under physiological and pathological conditions. Here, we investigated the relationship between DDC expression a ...[more]
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