Ontology highlight
ABSTRACT:
SUBMITTER: Alors-Perez E
PROVIDER: S-EPMC10767201 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Alors-Pérez Emilia E Pedraza-Arevalo Sergio S Blázquez-Encinas Ricardo R García-Vioque Víctor V Agraz-Doblas Antonio A Yubero-Serrano Elena M EM Sánchez-Frías Marina E ME Serrano-Blanch Raquel R Gálvez-Moreno María Ángeles MÁ Gracia-Navarro Francisco F Gahete Manuel D MD Arjona-Sánchez Álvaro Á Luque Raúl M RM Ibáñez-Costa Alejandro A Castaño Justo P JP
Molecular therapy. Nucleic acids 20231205 1
Pancreatic neuroendocrine tumors (PanNETs) comprise a heterogeneous group of tumors with growing incidence. Recent molecular analyses provided a precise picture of their genomic and epigenomic landscape. Splicing dysregulation is increasingly regarded as a novel cancer hallmark influencing key tumor features. We have previously demonstrated that splicing machinery is markedly dysregulated in PanNETs. Here, we aimed to elucidate the molecular and functional implications of <i>CUGBP ELAV-like fami ...[more]