Ontology highlight
ABSTRACT:
SUBMITTER: Gong TT
PROVIDER: S-EPMC10776562 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Gong Ting-Ting TT Liu Fang-Hua FH Xiao Qian Q Li Yi-Zi YZ Wei Yi-Fan YF Xu He-Li HL Cao Fan F Sun Ming-Li ML Jiang Feng-Li FL Tao Tao T Ma Qi-Peng QP Qin Xue X Song Yang Y Gao Song S Wu Lang L Zhao Yu-Hong YH Huang Dong-Hui DH Wu Qi-Jun QJ
Communications biology 20240109 1
Platinum-based chemotherapy remains one of the major choices for treatment of ovarian cancer (OC). However, primary or acquired drug resistance severely impairs their efficiency, thereby causing chemotherapy failure and poor prognosis. SH3 domain containing ring finger 2 (SH3RF2) has been linked to the development of cancer. Here we find higher levels of SH3RF2 in the tumor tissues from cisplatin-resistant OC patients when compared to those from cisplatin-sensitive patients. Similarly, cisplatin ...[more]