Ontology highlight
ABSTRACT:
SUBMITTER: Bisaccia P
PROVIDER: S-EPMC10785219 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Bisaccia Paola P Magarotto Fabio F D'Agostino Stefania S Dedja Arben A Barbon Silvia S Guidolin Diego D Liboni Cristina C Angioni Roberta R De Lazzari Giada G Caicci Federico F Viola Antonella A Jurga Marcin M Kundrotas Gabrielis G Stevens Dimitri D Mancuso Domenico D Gramegna Elisabetta E Seitaj Bruno B Kashyap Rudra R De Vos Beatrice B Macchi Veronica V Baraldi Eugenio E Porzionato Andrea A De Caro Raffaele R Muraca Maurizio M Pozzobon Michela M
Stem cells translational medicine 20240101 1
Oxidative stress and fibrosis are important stress responses that characterize bronchopulmonary dysplasia (BPD), a disease for which only a therapy but not a cure has been developed. In this work, we investigated the effects of mesenchymal stromal cells-derived extracellular vesicles (MSC-EVs) on lung and brain compartment in an animal model of hyperoxia-induced BPD. Rat pups were intratracheally injected with MSC-EVs produced by human umbilical cord-derived MSC, following the Good Manufacturing ...[more]