Dataset Information

Comparison of the effects of open and laparoscopic approach on body composition in gastrectomy for gastric cancer: A propensity score-matched study.

ABSTRACT:

Aim

To compare the effects of open (OG) and laparoscopic gastrectomy (LG) on body composition and muscle strength.

Methods

This study performed a propensity score matching analysis using cases from a large-scale, multicenter, phase III randomized controlled trial concerning oral nutritional supplements after gastrectomy and analyzed both the whole and matched cohorts. Measurements of body composition and hand grip strength (HGS) were performed at baseline (preoperatively) and at 1, 2, 3, 6, and 12 months after gastrectomy.

Results

Of 835 patients, 275 and 560 underwent OG and LG, respectively. Skeletal muscle mass (SMM) and HGS loss were significantly lesser in the LG group than in the OG group. The propensity score-matched analysis, including 120 pairs of patients, confirmed that the % SMM loss values at 1, 2, 3, 6, and 12 POM were -4.5%, -4.0%, -4.7%, -4.6%, and -5.8% in the OG group and -3.0%, -1.9%, -2.4%, -2.2%, and -2.7% in the LG group, respectively. The % SMM loss was significantly lesser in the LG group than in the OG group (repeated measures ANOVA p < 0.001). The HGS loss was non-significantly smaller in the LG group than in the OG group.

Conclusion

Skeletal muscle mass loss was significantly lesser in the LG group than in the OG group in both cohorts, indicating that LG may be more effective than OG for maintaining muscle mass.

SUBMITTER: Takeoka T

PROVIDER: S-EPMC10797822 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature

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Publications

Comparison of the effects of open and laparoscopic approach on body composition in gastrectomy for gastric cancer: A propensity score-matched study.

Takeoka Tomohira T Yamamoto Kazuyoshi K Kurokawa Yukinori Y Miyazaki Yasuhiro Y Kawabata Ryohei R Omori Takeshi T Imamura Hiroshi H Fujita Junya J Eguchi Hidetoshi H Doki Yuichiro Y

Annals of gastroenterological surgery 20230802 1

<h4>Aim</h4>To compare the effects of open (OG) and laparoscopic gastrectomy (LG) on body composition and muscle strength.<h4>Methods</h4>This study performed a propensity score matching analysis using cases from a large-scale, multicenter, phase III randomized controlled trial concerning oral nutritional supplements after gastrectomy and analyzed both the whole and matched cohorts. Measurements of body composition and hand grip strength (HGS) were performed at baseline (preoperatively) and at 1 ...[more]

PMID: 38250677

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Dataset Information

Comparison of the effects of open and laparoscopic approach on body composition in gastrectomy for gastric cancer: A propensity score-matched study.

Aim

Methods

Results

Conclusion

Publications

Comparison of the effects of open and laparoscopic approach on body composition in gastrectomy for gastric cancer: A propensity score-matched study.

Similar Datasets

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