Dataset Information

Prostate cancer management in Southeast Asian countries: a survey of clinical practice patterns.

ABSTRACT:

Background

Prostate cancer (PC) has a serious public health impact, and its incidence is rising due to the aging population. There is limited evidence and consensus to guide the management of PC in Southeast Asia (SEA). We present real-world data on clinical practice patterns in SEA for advanced PC care.

Method

A paper-based survey was used to identify clinical practice patterns and obtain consensus among the panelists. The survey included the demographics of the panelists, the use of clinical guidelines, and clinical practice patterns in the management of advanced PC in SEA.

Results

Most panelists (81%) voted prostate-specific antigen (PSA) as the most effective test for early PC diagnosis and risk stratification. Nearly 44% of panelists agreed that prostate-specific membrane antigen positron emission tomography-computed tomography imaging for PC diagnostic and staging information aids local and systemic therapy decisions. The majority of the panel preferred abiraterone acetate (67%) or docetaxel (44%) as first-line therapy for symptomatic mCRPC patients. Abiraterone acetate (50%) is preferred over docetaxel as a first-line treatment in metastatic castration-sensitive prostate cancer patients with high-volume disease. However, the panel did not support the use of abiraterone acetate in non-metastatic castration-resistant prostate cancer (nmCRPC) patients. Apalutamide (75%) is the preferred treatment option for patients with nmCRPC. The cost and availability of modern treatments and technologies are important factors influencing therapeutic decisions. All panelists supported the use of generic versions of approved therapies.

Conclusion

The survey results reflect real-world management of advanced PC in a SEA country. These findings could be used to guide local clinical practices and highlight the financial challenges of modern healthcare.

SUBMITTER: Chiong E

PROVIDER: S-EPMC10798109 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Prostate cancer management in Southeast Asian countries: a survey of clinical practice patterns.

Chiong Edmund E Saad Marniza M Hamid Agus Rizal A H ARAH Ong-Cornel Annielyn Beryl AB Lojanapiwat Bannakij B Pripatnanont Choosak C Serrano Dennis D Songco Jaime J Sin Loh Chit LC Hakim Lukman L Chua Melvin Lee Kiang MLK Nguyen Nguyen Phuc NP Phuong Pham Cam PC Patnaik Ravi Sekhar RS Umbas Rainy R Kanesvaran Ravindran R

Therapeutic advances in medical oncology 20240118

<h4>Background</h4>Prostate cancer (PC) has a serious public health impact, and its incidence is rising due to the aging population. There is limited evidence and consensus to guide the management of PC in Southeast Asia (SEA). We present real-world data on clinical practice patterns in SEA for advanced PC care.<h4>Method</h4>A paper-based survey was used to identify clinical practice patterns and obtain consensus among the panelists. The survey included the demographics of the panelists, the us ...[more]

PMID: 38249332

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Dataset Information

Prostate cancer management in Southeast Asian countries: a survey of clinical practice patterns.

Background

Method

Results

Conclusion

Publications

Prostate cancer management in Southeast Asian countries: a survey of clinical practice patterns.

Similar Datasets

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