The TGF-β Family in Glioblastoma.
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ABSTRACT:
SUBMITTER: Golan-Cancela I
PROVIDER: S-EPMC10816220 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Publications
The TGF-β Family in Glioblastoma.
Golán-Cancela Irene I Caja Laia L
International journal of molecular sciences 20240115 2
Members of the transforming growth factor β (TGF-β) family have been implicated in the biology of several cancers. In this review, we focus on the role of TGFβ and bone morphogenetic protein (BMP) signaling in glioblastoma. Glioblastoma (GBM) is the most common malignant brain tumor in adults; it presents at a median age of 64 years, but can occur at any age, including childhood. Unfortunately, there is no cure, and even patients undergoing current treatments (surgical resection, radiotherapy, a ...[more]
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