Ontology highlight
ABSTRACT:
SUBMITTER: Marques PH
PROVIDER: S-EPMC10817582 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Marques Pedro Henrique PH Tiwari Sandeep S Felice Andrei Giacchetto AG Jaiswal Arun Kumar AK Aburjaile Flávia Figueira FF Azevedo Vasco V Silva-Vergara Mario León ML Ferreira-Paim Kennio K Soares Siomar de Castro SC Fonseca Fernanda Machado FM
Journal of fungi (Basel, Switzerland) 20240105 1
Histoplasmosis is a widespread systemic disease caused by <i>Histoplasma capsulatum</i>, prevalent in the Americas. Despite its significant morbidity and mortality rates, no vaccines are currently available. Previously, five vaccine targets and specific epitopes for <i>H. capsulatum</i> were identified. Immunoinformatics has emerged as a novel approach for determining the main immunogenic components of antigens through in silico methods. Therefore, we predicted the main helper and cytotoxic T ly ...[more]