Ontology highlight
ABSTRACT:
SUBMITTER: Lefebvre V
PROVIDER: S-EPMC10819786 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Lefebvre Victor V Leon Foun Lin Ravy R Cole Laura L Cosset François-Loïc FL Fogeron Marie-Laure ML Böckmann Anja A
Viruses 20240105 1
One-third of the nine WHO shortlisted pathogens prioritized for research and development in public health emergencies belong to the <i>Bunyavirales</i> order. Several <i>Bunyavirales</i> species carry an NSm protein that acts as a virulence factor. We predicted the structures of these NSm proteins and unexpectedly found that in two families, their cytosolic domain was inferred to have a similar fold to that of the cytosolic domain of the viral envelope-forming glycoprotein N (Gn<sup>cyto</sup>) ...[more]