Ontology highlight
ABSTRACT:
SUBMITTER: Liu J
PROVIDER: S-EPMC10821240 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Liu Jie J Yang Jie J Pan Qilong Q Wang Xiangyu X Wang Xinyin X Chen Han H Zheng Xiaoling X Huang Qingling Q
European journal of medical research 20240127 1
MDM4 is one of the MDM protein family and is generally recognized as the key negative regulator of p53. As a cancer-promoting factor, it plays a non-negligible role in tumorigenesis and development. In this article, we analyzed the expression levels of MDM4 in pan-cancer through multiple databases. We also investigated the correlations between MDM4 expression and prognostic value, immune features, genetic mutation, and tumor-related pathways. We found that MDM4 overexpression is often accompanie ...[more]