Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC10825604 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Zhang Jiangang J Peng Shaodan S Xu Fang F Qiao Ying Y Ye Xiaoke X Guan Yu Y Zhao Xiaolong X Wang Yueran Y Shao Zhongqi Z Zhu Tao T Si Weixue W
Vaccine: X 20240106
Herpes zoster (HZ) induces significant pain and discomfort, which can seriously affect the quality of life of patients. At present, there is no specific treatment for HZ, and the mosteffective HZ control is vaccination. The main obstacle to developing an effective HZ vaccine is poorly induced cellular immune response. In this study, the IFN-α-gE-Fc fusion protein induced higher levels of humoral and cellular immunity compared to the unengineered gE antigen and higher levels of cellular immunity ...[more]