Ontology highlight
ABSTRACT:
SUBMITTER: Babb K
PROVIDER: S-EPMC1082833 | biostudies-literature | 2005 May
REPOSITORIES: biostudies-literature
Babb Kelly K von Lackum Kate K Wattier Rachel L RL Riley Sean P SP Stevenson Brian B
Journal of bacteriology 20050501 9
Defining the metabolic capabilities and regulatory mechanisms controlling gene expression is a valuable step in understanding the pathogenic properties of infectious agents such as Borrelia burgdorferi. The present studies demonstrated that B. burgdorferi encodes functional Pfs and LuxS enzymes for the breakdown of toxic products of methylation reactions. Consistent with those observations, B. burgdorferi was shown to synthesize the end product 4,5-dihydroxy-2,3-pentanedione (DPD) during laborat ...[more]