Extracellular release of antigenic proteins by Helicobacter pylori.
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ABSTRACT:
SUBMITTER: Cao P
PROVIDER: S-EPMC108299 | biostudies-literature | 1998 Jun
REPOSITORIES: biostudies-literature
Publications
Extracellular release of antigenic proteins by Helicobacter pylori.
Cao P P McClain M S MS Forsyth M H MH Cover T L TL
Infection and immunity 19980601 6
Screening a Helicobacter pylori genomic library with antisera raised against H. pylori broth culture supernatant resulted in the identification of six antigens: urease, HspB, Lpp20, DnaK, MsrA, and a cysteine-rich 28-kDa protein (designated HcpA). H. pylori antigens may be released into the extracellular space by multiple mechanisms, including specific secretion pathways, autolysis, and membrane vesicle formation. ...[more]
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