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Identification of an insertion sequence located in a region encoding virulence factors of Streptococcus pyogenes.

ABSTRACT: An insertion sequence, IS1562, was identified in a Streptococcus pyogenes strain of the clinically important M1 serotype. IS1562 is located in the mga regulon between the genes coding for the M protein and the C5a peptidase, both important virulence factors. The same or similar insertion sequences were found in most S. pyogenes strains, but the chromosomal location differed among isolates.

SUBMITTER: Berge A

PROVIDER: S-EPMC108369 | biostudies-literature | 1998 Jul

REPOSITORIES: biostudies-literature

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Identification of an insertion sequence located in a region encoding virulence factors of Streptococcus pyogenes.

Berge A A Rasmussen M M Björck L L

Infection and immunity 19980701 7

An insertion sequence, IS1562, was identified in a Streptococcus pyogenes strain of the clinically important M1 serotype. IS1562 is located in the mga regulon between the genes coding for the M protein and the C5a peptidase, both important virulence factors. The same or similar insertion sequences were found in most S. pyogenes strains, but the chromosomal location differed among isolates. ...[more]

PMID: 9632622

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