Ontology highlight
ABSTRACT: Background
Robust data comparing long COVID in hospitalized and non-hospitalized patients in middle-income countries are limited.Methods
A retrospective cohort study was conducted in Brazil, including hospitalized and non-hospitalized patients. Long COVID was diagnosed at 90-day follow-up using WHO criteria. Demographic and clinical information, including the depression screening scale (PHQ-2) at day 30, was compared between the groups. If the PHQ-2 score is 3 or greater, major depressive disorder is likely. Logistic regression analysis identified predictors and protective factors for long COVID.Results
A total of 291 hospitalized and 1,118 non-hospitalized patients with COVID-19 were included. The prevalence of long COVID was 47.1% and 49.5%, respectively. Multivariable logistic regression showed female sex (odds ratio [OR] = 4.50, 95% confidence interval (CI) 2.51-8.37), hypertension (OR = 2.90, 95% CI 1.52-5.69), PHQ-2 > 3 (OR = 6.50, 95% CI 1.68-33.4) and corticosteroid use during hospital stay (OR = 2.43, 95% CI 1.20-5.04) as predictors of long COVID in hospitalized patients, while female sex (OR = 2.52, 95% CI 1.95-3.27) and PHQ-2 > 3 (OR = 3.88, 95% CI 2.52-6.16) were predictors in non-hospitalized patients.Conclusion
Long COVID was prevalent in both groups. Positive depression screening at day 30 post-infection can predict long COVID. Early screening of depression helps health staff to identify patients at a higher risk of long COVID, allowing an early diagnosis of the condition.
SUBMITTER: Malheiro DT
PROVIDER: S-EPMC10839020 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Malheiro Daniel Tavares DT Bernardez-Pereira Sabrina S Parreira Kauê Capellato Junqueira KCJ Pagliuso João Gabriel Dias JGD de Paula Gomes Emerson E de Mesquita Escobosa Daisa D de Araújo Carolina Ivo CI Pimenta Beatriz Silva BS Lin Vivian V de Almeida Silvana Maria SM Tuma Paula P Laselva Claudia Regina CR Neto Miguel Cendoroglo MC Klajner Sidney S Teich Vanessa Damazio VD Kobayashi Takaaki T Edmond Michael B MB Marra Alexandre R AR
Frontiers in public health 20240122
<h4>Background</h4>Robust data comparing long COVID in hospitalized and non-hospitalized patients in middle-income countries are limited.<h4>Methods</h4>A retrospective cohort study was conducted in Brazil, including hospitalized and non-hospitalized patients. Long COVID was diagnosed at 90-day follow-up using WHO criteria. Demographic and clinical information, including the depression screening scale (PHQ-2) at day 30, was compared between the groups. If the PHQ-2 score is 3 or greater, major d ...[more]