Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC10844451 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
Zhang Jiaqian J Liu Hongjiang H Chen Yuehong Y Liu Huan H Zhang Shengxiao S Yin Geng G Xie Qibing Q
Frontiers in immunology 20240123
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune condition marked by inflammation of the joints, degradation of the articular cartilage, and bone resorption. Recent studies found the absolute and relative decreases in circulating regulatory T cells (Tregs) in RA patients. Tregs are a unique type of cells exhibiting immunosuppressive functions, known for expressing the Foxp3 gene. They are instrumental in maintaining immunological tolerance and preventing autoimmunity. Increasing the a ...[more]