Ontology highlight
ABSTRACT:
SUBMITTER: Großmann NL
PROVIDER: S-EPMC10855893 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Großmann Nora L NL Weihs Antoine A Kühn Luise L Sauer Susann S Röh Simone S Wiechmann Tobias T Rex-Haffner Monika M Völzke Henry H Völker Uwe U Binder Elisabeth B EB Teumer Alexander A Homuth Georg G Klinger-König Johanna J Grabe Hans J HJ
International journal of molecular sciences 20240125 3
Childhood maltreatment is an important risk factor for adult depression and has been associated with changes in the hypothalamic pituitary adrenal (HPA) axis, including cortisol secretion and methylation of the <i>FKBP5</i> gene. Furthermore, associations between depression and HPA changes have been reported. This study investigated the associations of whole-blood <i>FKBP5</i> mRNA levels, serum cortisol levels, childhood maltreatment, and depressive symptoms with the whole-blood methylation sta ...[more]