Ontology highlight
ABSTRACT:
SUBMITTER: Shiwarski DJ
PROVIDER: S-EPMC10862740 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
bioRxiv : the preprint server for biology 20240130
Microfluidic and organ-on-a-chip devices have improved the physiologic and translational relevance of in vitro systems in applications ranging from disease modeling to drug discovery and pharmacology. However, current manufacturing approaches have limitations in terms of materials used, non-native mechanical properties, patterning of extracellular matrix (ECM) and cells in 3D, and remodeling by cells into more complex tissues. We present a method to 3D bioprint ECM and cells into microfluidic co ...[more]