Transforming research to improve therapies for trauma in the twenty-first century.
Ontology highlight
ABSTRACT:
SUBMITTER: Juffermans NP
PROVIDER: S-EPMC10865682 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
Publications
Transforming research to improve therapies for trauma in the twenty-first century.
Juffermans Nicole P NP Gözden Tarik T Brohi Karim K Davenport Ross R Acker Jason P JP Reade Michael C MC Maegele Marc M Neal Matthew D MD Spinella Philip C PC
Critical care (London, England) 20240213 1
Improvements have been made in optimizing initial care of trauma patients, both in prehospital systems as well as in the emergency department, and these have also favorably affected longer term outcomes. However, as specific treatments for bleeding are largely lacking, many patients continue to die from hemorrhage. Also, major knowledge gaps remain on the impact of tissue injury on the host immune and coagulation response, which hampers the development of interventions to treat or prevent organ ...[more]
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