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Helicobacter pylori-Negative Gastric Mucosa-Associated Lymphoid Tissue Lymphoma in a Girl.


ABSTRACT:

Introduction

Extranodal marginal zone lymphoma (MZL) arises in a number of epithelial tissues, including the stomach, salivary gland, lung, small bowel, thyroid, ocular adnexa, skin, and elsewhere. It has also been called low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). MALT lymphoma predominantly occurs in adults and is rare in children.

Case presentation

We report a case of MALT lymphoma involving the stomach, which is the most common subtype, in a 12-year-old girl. Initially, the patient relapsed after antibiotic therapy but achieved successful treatment subsequently through irradiation.

Conclusion

Helicobacter pylori eradication therapy should be given to all patients with gastric MZL, irrespective of stage. In patients who do not respond to antibiotic therapy, treatment options such as irradiation and systemic cancer therapies should be considered, depending on the disease stage.

SUBMITTER: Pham NH 

PROVIDER: S-EPMC10869146 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature

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<i>Helicobacter pylori</i>-Negative Gastric Mucosa-Associated Lymphoid Tissue Lymphoma in a Girl.

Pham Nhu Hiep NH   Phan Canh Duy CD   Dang An A   Tran Kiem Hao KH   Chau Van Ha VH   Nguyen Thi Kim Hoa KH   Nguyen Thi My Linh ML   Dang Thi Tam TT   Nguyen Linh Giang LG  

Case reports in oncology 20240101 1


<h4>Introduction</h4>Extranodal marginal zone lymphoma (MZL) arises in a number of epithelial tissues, including the stomach, salivary gland, lung, small bowel, thyroid, ocular adnexa, skin, and elsewhere. It has also been called low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). MALT lymphoma predominantly occurs in adults and is rare in children.<h4>Case presentation</h4>We report a case of MALT lymphoma involving the stomach, which is the most common subtype, in a 12-year-  ...[more]

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