Project description:Facioscapulohumeral muscular dystrophy (FSHD) is the second most common genetic myopathy, characterized by slowly progressing and highly heterogeneous muscle wasting with a typical onset in the late teens/early adulthood [1]. Although the etiology of the disease for both FSHD type 1 and type 2 has been attributed to gain-of-toxic function stemming from aberrant DUX4 expression, the exact pathogenic mechanisms involved in muscle wasting have yet to be elucidated [2-4]. The 2021 FSHD International Research Congress, held virtually on June 24-25, convened over 350 researchers and clinicians to share the most recent advances in the understanding of the disease mechanism, discuss the proliferation of interventional strategies and refinement of clinical outcome measures, including results from the ReDUX4 trial, a phase 2b clinical trial of losmapimod in FSHD [NCT04003974].

| S-EPMC8762812 | biostudies-literature

Meeting report: the 2020 FSHD International Research Congress.

Project description: Not available

| S-EPMC7721607 | biostudies-literature

CIMT 2023: report on the 20th Annual Meeting of the Association for Cancer Immunotherapy.

Project description:The Association for Cancer Immunotherapy (CIMT) celebrated the 20th anniversary of the CIMT Annual Meeting. CIMT2023 was held 3-5 May 2023 in Mainz, Germany. 1051 academic and clinical professionals from over 30 countries attended the meeting and discussed the latest advances in cancer immunology and immunotherapy research. This report summarizes the highlights of CIMT2023.

| S-EPMC10590812 | biostudies-literature

Proceedings of Reanimation 2023, the French Intensive Care Society International Congress.

Project description: Not available

| S-EPMC10264219 | biostudies-literature

ERS International Congress 2023: highlights from the Pulmonary Vascular Diseases Assembly.

Project description:Pulmonary vascular diseases such as pulmonary embolism and pulmonary hypertension are important and frequently under-recognised conditions. This article provides an overview of key highlights in pulmonary vascular diseases from the European Respiratory Society International Congress 2023. This includes insights into disease modification in pulmonary arterial hypertension and novel therapies such as sotatercept and seralutinib. Exciting developments in our understanding of the mechanisms underpinning pulmonary hypertension associated with interstitial lung disease are also explored. A comprehensive overview of the complex relationship between acute pulmonary embolism and chronic thromboembolic pulmonary hypertension (CTEPH) is provided along with our current understanding of the molecular determinants of CTEPH. The importance of multidisciplinary and holistic care cannot be understated, and this article also addresses advances beyond medication, with a special focus on exercise training and rehabilitation.

| S-EPMC10895433 | biostudies-literature

The Congress of the International Association of Rural Medicine (IARM 2023)

Project description: Not available

| S-EPMC11222618 | biostudies-literature

ERS International Congress 2023: highlights from the Interstitial Lung Diseases Assembly.

Project description:This article summarises a selection of scientific highlights in the field of interstitial lung diseases (ILDs) presented at the International Congress of the European Respiratory Society in 2023. Translational and clinical studies focused on the whole spectrum of ILDs, from (ultra)rare ILDs to sarcoidosis, ILDs associated with connective tissue disease and idiopathic pulmonary fibrosis. The main topics of the 2023 Congress presentations were improving the diagnostic process of ILDs, better prediction of disease course and investigation of novel treatment options.

| S-EPMC10962449 | biostudies-literature

Abstracts of the XIX International Congress of Neuropathology, Tokyo, Japan, September 23-27, 2018.

Project description: Not available

| S-EPMC8028628 | biostudies-literature