Ontology highlight
ABSTRACT:
SUBMITTER: Cao SQ
PROVIDER: S-EPMC10908791 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Cao Shi-Qiang SQ Xue Song-Tao ST Li Wen-Juan WJ Hu Guo-Sheng GS Wu Zhi-Gang ZG Zheng Jian-Cong JC Zhang Shu-Liang SL Lin Xiao X Chen Chun C Chen Chun C Liu Wen W Zheng Bin B
Cell death discovery 20240302 1
The oncogenic role of circRNA in cancers including esophageal cancer (EC) has been well studied. However, whether and how circRNAs are involved in cancer cell metabolic processes remains largely unknown. Here, we reported that circRNA, circHIPK3, is highly expressed in ESCC cell lines and tissues. Knockdown of circHIPK3 significantly restrained cell proliferation, colony formation, migration, and invasion in vitro and inhibited tumor growth in vivo. Mechanistically, circHIPK3 was found to act as ...[more]