Ontology highlight
ABSTRACT:
SUBMITTER: Sone K
PROVIDER: S-EPMC10908842 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Sone Kazuki K Sakamaki Yuka Y Hirose Satomi S Inagaki Mai M Tachikawa Masanori M Yoshino Daisuke D Funamoto Kenichi K
Scientific reports 20240302 1
Blood glucose levels fluctuate during daily life, and the oxygen concentration is low compared to the atmosphere. Vascular endothelial cells (ECs) maintain vascular homeostasis by sensing changes in glucose and oxygen concentrations, resulting in collective migration. However, the behaviors of ECs in response to high-glucose and hypoxic environments and the underlying mechanisms remain unclear. In this study, we investigated the collective migration of ECs simultaneously stimulated by changes in ...[more]