Ontology highlight
ABSTRACT:
SUBMITTER: Claes K
PROVIDER: S-EPMC10914597 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Claes Katrien K Van Herpe Dries D Vanluchene Robin R Roels Charlotte C Van Moer Berre B Wyseure Elise E Vandewalle Kristof K Eeckhaut Hannah H Yilmaz Semiramis S Vanmarcke Sandrine S Çıtak Erhan E Fijalkowska Daria D Grootaert Hendrik H Lonigro Chiara C Meuris Leander L Michielsen Gitte G Naessens Justine J van Schie Loes L De Rycke Riet R De Bruyne Michiel M Borghgraef Peter P Callewaert Nico N
Nature microbiology 20240304 3
The industrial yeast Komagataella phaffii (formerly named Pichia pastoris) is commonly used to synthesize recombinant proteins, many of which are used as human therapeutics or in food. However, the basic strain, named NRRL Y-11430, from which all commercial hosts are derived, is not available without restrictions on its use. Comparative genome sequencing leaves little doubt that NRRL Y-11430 is derived from a K. phaffii type strain deposited in the UC Davis Phaff Yeast Strain Collection in 1954. ...[more]