Ontology highlight
ABSTRACT:
SUBMITTER: Kaur D
PROVIDER: S-EPMC10919401 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Kaur Diljeet D Lee Sol Moe SM Goldberg David D Spix Nathan J NJ Hinoue Toshinori T Li Hong-Tao HT Dwaraka Varun B VB Smith Ryan R Shen Hui H Liang Gangning G Renke Nicole N Laird Peter W PW Zhou Wanding W
Epigenetics communications 20230927 1
Infinium Methylation BeadChips are widely used to profile DNA cytosine modifications in large cohort studies for reasons of cost-effectiveness, accurate quantification, and user-friendly data analysis in characterizing these canonical epigenetic marks. In this work, we conducted a comprehensive evaluation of the updated Infinium MethylationEPIC v2 BeadChip (EPICv2). Our evaluation revealed that EPICv2 offers significant improvements over its predecessors, including expanded enhancer coverage, ap ...[more]