Ontology highlight
ABSTRACT:
SUBMITTER: Lethe MCL
PROVIDER: S-EPMC10932239 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
Lethe Mary Caroline L MCL Paris Vincent V Wang Xiaoqiang X Chan Clement T Y CTY
International journal of molecular sciences 20240228 5
The uridine diphosphate glycosyltransferase (UGT) superfamily plays a key role in the metabolism of xenobiotics and metabolic wastes, which is essential for detoxifying those species. Over the last several decades, a huge effort has been put into studying human and mammalian UGT homologs, but family members in other organisms have been explored much less. Potentially, other UGT homologs can have desirable substrate specificity and biological activities that can be harnessed for detoxification in ...[more]