Ontology highlight
ABSTRACT:
SUBMITTER: Matsui Y
PROVIDER: S-EPMC10948829 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Matsui Yuichi Y Muramatsu Fumitaka F Nakamura Hajime H Noda Yoshimi Y Matsumoto Kinnosuke K Kishima Haruhiko H Takakura Nobuyuki N
Communications biology 20240318 1
Whether organ-specific regeneration is induced by organ-specific endothelial cells (ECs) remains unelucidated. The formation of white matter lesions due to chronic cerebral hypoperfusion causes cognitive decline, depression, motor dysfunction, and even acute ischemic stroke. Vascular ECs are an important target for treating chronic cerebral hypoperfusion. Brain-derived ECs transplanted into a mouse chronic cerebral hypoperfusion model showed excellent angiogenic potential. They were also associa ...[more]