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Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report.


ABSTRACT:

Introduction

This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare.

Case presentation

Solitary metastasis presented as a solid mass in the central third of the upper eyelid, which has been growing for 3 weeks. Treatment included tumor removal and blepharoplasty. Histopathological examination showed metastasis of clear cell renal carcinoma. A thorough examination revealed a primary tumor on the lower pole of the right kidney. A right nephrectomy was performed, and histopathology showed ccRCC. Postoperative examinations showed no signs of local or systemic disease. Sunitinib malate was administered to the patient.

Conclusion

The eyelid metastasis in this case was still solitary and had been discovered before the existence of the primary tumor was known. Ocular metastasis of renal carcinoma is a rare initial manifestation of the disease and therefore requires a multidisciplinary approach in the treatment of these patients.

SUBMITTER: Zrinscak O 

PROVIDER: S-EPMC10950357 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature

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Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report.

Zrinšćak Ognjen O   Kasumović Armin A   Krolo Iva I   Ivekovic Renata R   Malenica Ravlić Maja M   Tomašković Igor I   Vatavuk Zoran Z  

Case reports in oncology 20240101 1


<h4>Introduction</h4>This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare.<h4>Case presentation</h4>Solitary metastasis presented as a solid mass in the central third of the upper eyelid, which has been growing for 3 weeks. Treatment included tumor removal and blepharoplasty. Histopathological e  ...[more]

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