Ontology highlight
ABSTRACT:
SUBMITTER: Yagi R
PROVIDER: S-EPMC10957877 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Yagi Ryuichiro R Goto Shinichi S Himeno Yukihiro Y Katsumata Yoshinori Y Hashimoto Masahiro M MacRae Calum A CA Deo Rahul C RC
Nature communications 20240321 1
Anthracyclines can cause cancer therapy-related cardiac dysfunction (CTRCD) that adversely affects prognosis. Despite guideline recommendations, only half of the patients undergo surveillance echocardiograms. An AI model detecting reduced left ventricular ejection fraction from 12-lead electrocardiograms (ECG) (AI-EF model) suggests ECG features reflect left ventricular pathophysiology. We hypothesized that AI could predict CTRCD from baseline ECG, leveraging the AI-EF model's insights, and deve ...[more]