Ontology highlight
ABSTRACT:
SUBMITTER: Belshan M
PROVIDER: S-EPMC109674 | biostudies-literature | 1998 May
REPOSITORIES: biostudies-literature
Journal of virology 19980501 5
Sequence analysis identified significant variation in the second exon of equine infectious anemia virus (EIAV) rev. Functional analysis indicated that limited amino acid variation in Rev significantly altered the export activity of the protein but did not affect Rev-dependent alternative splicing. EIAV Rev can mediate export through two independent cis-acting Rev-responsive elements (RREs), and differences among Rev variants were more pronounced when both RREs were present. Variation in Rev may ...[more]