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Molecular evidence for nosocomial transmission of human immunodeficiency virus from a surgeon to one of his patients.

ABSTRACT: We have investigated the molecular evidence in favor of the transmission of human immunodeficiency virus (HIV) from an HIV-infected surgeon to one of his patients. After PCR amplification, the env and gag sequences from the viral genome were cloned and sequenced. Phylogenetic analysis revealed that the viral sequences derived from the surgeon and his patient are closely related, which strongly suggests that nosocomial transmission occurred. In addition, these viral sequences belong to group M of HIV type 1 but are divergent from the reference sequences of the known subtypes.

SUBMITTER: Blanchard A

PROVIDER: S-EPMC109704 | biostudies-literature | 1998 May

REPOSITORIES: biostudies-literature

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Molecular evidence for nosocomial transmission of human immunodeficiency virus from a surgeon to one of his patients.

Blanchard A A Ferris S S Chamaret S S Guétard D D Montagnier L L

Journal of virology 19980501 5

We have investigated the molecular evidence in favor of the transmission of human immunodeficiency virus (HIV) from an HIV-infected surgeon to one of his patients. After PCR amplification, the env and gag sequences from the viral genome were cloned and sequenced. Phylogenetic analysis revealed that the viral sequences derived from the surgeon and his patient are closely related, which strongly suggests that nosocomial transmission occurred. In addition, these viral sequences belong to group M of ...[more]

PMID: 9557756

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