Ontology highlight
ABSTRACT:
SUBMITTER: Ranjan K
PROVIDER: S-EPMC10970579 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Ranjan Kishu K Pathak Chandramani C
International journal of molecular sciences 20240312 6
Fas-associated death domain (FADD) is an adaptor protein that predominantly transduces the apoptosis signal from the death receptor (DR) to activate caspases, leading to the initiation of apoptotic signaling and the coordinated removal of damaged, infected, or unwanted cells. In addition to its apoptotic functions, FADD is involved in signaling pathways related to autophagy, cell proliferation, necroptosis, and cellular senescence, indicating its versatile role in cell survival and proliferation ...[more]