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Understanding the impact of adult pertussis and current approaches to vaccination: A narrative review and expert panel recommendations.

ABSTRACT: Pertussis has several notable consequences, causing economic burden, increased strain on healthcare facilities, and reductions in quality of life. Recent years have seen a trend toward an increase in pertussis cases affecting older children and adults. To boost immunity, and protect vulnerable populations, an enduring approach to vaccination has been proposed, but gaps remain in the evidence surrounding adult vaccination that are needed to inform such a policy. Gaps include: the true incidence of pertussis and its complications in adults; regional variations in disease recognition and reporting; and incidence of severe disease, hospitalizations, and deaths in older adults. Better data on the efficacy/effectiveness of pertussis vaccination in adults, duration of protection, and factors leading to poor vaccine uptake are needed. Addressing the critical evidence gaps will help highlight important areas of unmet need and justify the importance of adult pertussis vaccination to healthcare professionals, policymakers, and payers.

SUBMITTER: Kardos P

PROVIDER: S-EPMC10989709 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature

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Understanding the impact of adult pertussis and current approaches to vaccination: A narrative review and expert panel recommendations.

Kardos Peter P Correia de Sousa Jaime J Heininger Ulrich U Konstantopoulos Andreas A MacIntyre C Raina CR Middleton Donald D Nolan Terry T Papi Alberto A Rendon Adrian A Rizzo Albert A Sampson Kim K Sette Alessandro A Sobczyk Elizabeth E Tan Tina T Weil-Olivier Catherine C Weinberger Birgit B Wilkinson Tom T Wirsing von König Carl Heinz CH

Human vaccines & immunotherapeutics 20240402 1

Pertussis has several notable consequences, causing economic burden, increased strain on healthcare facilities, and reductions in quality of life. Recent years have seen a trend toward an increase in pertussis cases affecting older children and adults. To boost immunity, and protect vulnerable populations, an enduring approach to vaccination has been proposed, but gaps remain in the evidence surrounding adult vaccination that are needed to inform such a policy. Gaps include: the true incidence o ...[more]

PMID: 38564339

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Dataset Information

Understanding the impact of adult pertussis and current approaches to vaccination: A narrative review and expert panel recommendations.

Publications

Understanding the impact of adult pertussis and current approaches to vaccination: A narrative review and expert panel recommendations.

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